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BIOM5001 / BMG5101 - Engineering Analysis and Modelling of Human Anatomy and Physiology

NOTE: This is the outline for the Fall 2008 course.


Engineering systems approaches to analysis and modelling of human anatomy and physiology. Mechanical and electrical properties of tissues. Muscoskeletal, cardiovascular and pulmonary systems.


    Engineering undergraduate program


Times and Locations

Fall 2008     (Sept 4 − Dec 3)

Section  Activity  Day  Location 
BIOM5001    LEC 1    Tuesday 16:00 - 19:00    Marion Hall 223   

Text and Notes

  • Gholamreza Rouhi
    • Biomechanics of Musculoskeletal System #1
    • Biomechanics of Musculoskeletal System #2
    • D.L. Bartel, D.T. Davy and T.M. Keaveney, Orthopaedic Biomechanics, Mechanics and Design in Musculoskeletal Systems, Prentice Hall, 2006.
    • M. Nordin and V.H. Frankel, Basic Biomechanics of the Musculoskeletal System, 3rd edition, Lippincott Williams & Wilkins, 2001.
    • S.C. Cowin, Bone Mechanics Handbook, 2nd Edition, CRC Press, 2001.
  • Adrian Chan
    • Matthews G. G., Cellular Physiology of Nerve and Muscle, 4th edition, Blackwell Publishing, Malden MA, USA, 2003.
    • Rangayyan, R. M., Biomedical Signal Analysis A Case-Study Approach, IEEE Press/Wiley, New York, NY, USA, 2002.
    • Malmvuo J, Plonsey, Bioelectromagnetism: Principles and Application of Bioelectric and Biomagnetic Fields, Oxford University Press, New York, NY, USA, 1995.
    • Webster JG, Medical Instrumentation: Application and Design, 3rd Edition, Wiley & Sons, 1997.
  • Andy Adler


Work     Value
Assignments     − Oct. 21 (7.5%)
− Nov. 11 (7.5%)
− Dec. 2 (7.5%)

Quizzes − Sep. 23 (7.5%)    7.5%

Report     − Proposal (Sept. 30)    (2%)
− Detailed Outline (Oct. 28)    (3%)
− Final Report (Nov. 25)    (15%)

Final Exam    50%


    Assignments are due at the beginning of class on the date indicated. Each assignment or quiz is worth 7.5% of the final grade.

    No.  Assignment  Due Date
    1   Assign #1   Oct. 21

    2   Assign #2   Nov. 11

    3     Dec. 2


    Each student will be required to submit a report on an aspect of human anatomy and physiology that is not part of the course outline. The goal of the report is to help students to explore the breadth of anatomy and physiology. The report will pick a particular anatomical system and explore it in term of its function in health and disease. Students are encouraged to focus on physiological models of performance and function of each system. Reports may briefly consider therapies and design of artificial organs, but must be primarily focussed on systems physiology and anatomy.

    Reports will be graded for 1) clarity and interest of presentation (50% of mark), and 2) technical content (50% of mark). Technical content should be on system anatomy and physiology including simple engineering model(s) of the selected system.

    The proposal is due Sept 30. It should be approx 300 words.

    The detailed outline is due Oct 28. It should describe the main points of the report, and give a list of references.

    The report is due Nov. 25. It should be be 15−20 pages (12pt double spaced) including figures and references.

Exams (Quizzes and Final)

  • Final Exam will be three hours on Dec. 16.
  • The final exam will have 4 sections, corresponding to each instructor. The weighting (based on performance on each section) will be: 35% (best mark), 25%, 25%, 15% (lowest mark)
  • One quizzes will be given (in class) during the term. The quiz will take about 30 minutes and is worth 7.5% of the final mark.
  • For all exams and quizzes, you will be permitted a calculator and one (1) 8.5" × 11" paper sheet containing any information you choose (double sided). Only non-programmable calculators may be used.

Course Outline

Date   Activity  
Sept. 9
Sept. 16
Sept. 23
  Anatomy and physiology of the musculo-skeletal system. Mechanical behaviour of hard tissues, articular cartilage and skeletal muscle. Analysis and modelling of the mechanical behaviour of hard tissues articular cartilage and skeletal muscle
Instructor: Gholamreza Rouhi

Sept. 30
Oct. 7
Oct. 14
  Electrical properties of tissue, Neuromuscular system
− Electrical properties of tissues: Nerve and Muscle cells
− Anatomy and physiology of the nervous system
− Bioelectrical Signals: EMG, ECG, EEG
Instructor: Adrian Chan

Oct. 21
Oct. 28
Nov. 4
  Pulmonary system
− Anatomy and physiology of lung and lung tissue
− Mechanical models of lung tissue in health and disease
− Gas transport models of lung tissue in health and disease
− Measures of lung function
Instructor: Andy Adler

Nov. 11
Nov. 18
Nov. 25
  Anatomy and physiology of the cardiovascular system. Mechanical behaviour of soft tissues. Analysis and modelling of the mechanical behaviour of soft tissues (including blood vessels). Non-linear elastic behaviour.
Instructor: Michel Labrosse

Dec. 2   Review of previous year's exam (For Q#2: delete "and its effect on the transmembrane potential is negligible", and change "What is the intracellular concentration of Cl-" to "What is the intracellular concentration of Na+")
Reports Due
Dec. 16   Final Exam: 16h00 to 19h00. Location is CBY D103

Other information

  • Late work policy:
     ≤ 7 days late: 20% off
     > 7 days late: zero mark.
  • If you have a question about a mark you have received, fill out, sign and submit this form.
  • Academic fraud will be taken very seriously. Cooperation between students for assignments is expected and encouraged, however, copying of another's work is not. You should not be leaving a discussion with copies of another student's work. Please refer to the University of Ottawa policies on this subject.

Last Updated: $Date: 2009-08-12 15:55:40 -0400 (Wed, 12 Aug 2009) $